Searchable abstracts of presentations at key conferences in endocrinology

ea0015p136 | Diabetes, metabolism and cardiovascular | SFEBES2008

The influence of birth weight on glucocorticoid receptor (GCR) expression in skeletal muscle of neonatal pigs

Williams Paula , Litten Jenny , Corson Anne , Clarke Lynne , Symonds Michael , Mostyn Alison

Background: Size at birth has been shown to have important consequences on later health, including the development of the metabolic syndrome. Tissue sensitivity to cortisol is regulated, in part, by the GCR and alterations in GCR expression have been observed in obesity and type 2 diabetes.Objectives: To examine whether birth weight influences the expression of GCR mRNA in skeletal muscle (SM) at days 7 and 14 of postnatal life.Met...