ea0015p136 | Diabetes, metabolism and cardiovascular | SFEBES2008
Williams Paula
, Litten Jenny
, Corson Anne
, Clarke Lynne
, Symonds Michael
, Mostyn Alison
Background: Size at birth has been shown to have important consequences on later health, including the development of the metabolic syndrome. Tissue sensitivity to cortisol is regulated, in part, by the GCR and alterations in GCR expression have been observed in obesity and type 2 diabetes.Objectives: To examine whether birth weight influences the expression of GCR mRNA in skeletal muscle (SM) at days 7 and 14 of postnatal life.Met...